About the UK Cystic Fibrosis Gene Therapy Consortium

The Consortium groups are based in three of the leading UK universities. Prior to the formation of the Consortium each group had conducted at least one clinical trial for gene therapy. Therefore, our researchers have been at the forefront of this field for over 20 years.

These sections describe the how the Consortium functions and how we are organised.

Together against CF

In 2001 the UK's three UK's three leading Cystic Fibrosis gene therapy groups joined together as one organisation, the UKCFGTC, to share expertise and funding.

Aim

The aim of this collaboration was to bring the three research groups together to focus on a single common goal of making gene therapy for CF a clinical reality.

Progress

The Consortium is now the world's largest gene therapy group focused on a single disease, with a combined staff of over 50. Our clinical trial programme is well underway and there are plans to initiate a multi-dose study of our first clinical product in 2012.

This multi-dose trial will be the first ever opportunity to find out if our gene therapy can result in clinical benefit.

Consortium Members

University of Oxford: Gene Medicine Group

University of Edinburgh: Centre for Molecular Medicine and Roslin Institute

Imperial College London: Department of Gene Therapy, National Heart & Lung Institute

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The CF Trust

 

Information for Patients on Our Clinical Trial
Latest Clinical Trial News
Contact Details
Patient Identification Centres
Frequently Asked Questions

 

Consortium Members' Internal Website
About Us
How the Consortium Works
Profiles of the Strategy Group
Milestones
Community Review
Prof David Porteous OBE
Oxford University Gene Medicine
Centre for Molecular Medicine, Edinburgh
The Roslin Institute
Dep of Gene Therapy, Imperial

 

Our Research
Optimisation of pDNA
Aerosol Delivery
Viral Vectors Development
Assay Development
Core Facilities
Consortium Patents

 

Clinical Programme
GL67A/pGM169
Clinical Team
Tracking Study
The Run-in Study
Single Dose Clinical Trial
Multi Dose Clinical Trial

 

Cystic Fibrosis
What is CF?
History of CF
Discovery of the CFTR Gene
What Causes CF?
CFTR Protein Structure
Cystic Fibrosis Links

 

Funding
EME
DPFS
Gene Therapy
Introduction to CF Gene Therapy
Why use Gene Therapy for CF?
Other CF Gene Therapy Groups
Examples of Successful Gene Therapy
Gene Therapy Links

 

Publications
Publications in Journals
Conference Posters & Presentations
JustGeneTherapy Lecture, Sept 2012
Book Chapters
Lectures
Open Access Publications
Latest Publications

 

Medical Futures Innovation Award 2011
Introductory Video
What is a Lentivirus
Production of Lentiviruses
Progress to Date
DNAVec
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