Presentation of Multi Dose Clinical Trial Results (2015): Prof Eric Alton presents the data from our MD clinical trial to an invited audience from the UK CF community. May 30 2015, Imperial College, London.
Proposed 3D model of the CFTR protein.
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)
DNA fragments being cut from an agarose gel exposed to UV.
A cake that only some of us got to enjoy!
Pellets of DNA following precipitation.
Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).
A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.
Schematic diagram of the large human airways.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).
Large scale lentivirus production in suspension culture.