Presentation of Multi Dose Clinical Trial Results (2015): Prof Eric Alton presents the data from our MD clinical trial to an invited audience from the UK CF community. May 30 2015, Imperial College, London.
DNA fragments being cut from an agarose gel exposed to UV.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
Proposed 3D model of the CFTR protein.
A cake that only some of us got to enjoy!
Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).
Purifying mRNA from tissue samples.
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).
A CFTR Western blot, to confirm protein production in cell culture.
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)
Large scale lentivirus production in suspension culture.
A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.
Schematic diagram of the large human airways.
Pellets of DNA following precipitation.