Presentation of Multi Dose Clinical Trial Results (2015): Prof Eric Alton presents the data from our MD clinical trial to an invited audience from the UK CF community. May 30 2015, Imperial College, London.
Large scale lentivirus production in suspension culture.
Pellets of DNA following precipitation.
DNA fragments being cut from an agarose gel exposed to UV.
A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
Purifying mRNA from tissue samples.
Proposed 3D model of the CFTR protein.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)
Schematic diagram of the large human airways.
Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).
A cake that only some of us got to enjoy!
A CFTR Western blot, to confirm protein production in cell culture.