Four Consortium Abstracts at the 2015 ASGCT Conference

Monday, April 27th 2015

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ASGCT_Logo.jpgThe 18th American Society of Gene & Cell Therapy Conference takes place in New Orleans next month (13 to 16 May). The Conference has become the main global event for the gene therapy community with around 2500 scientists and clinicians attending. A small group of Consortium scientists are heading out to represent us. 

They will be presenting four abstracts covering various aspects of our work. Dr Steve Hyde will present a talk on our large scale production of lentiviral vectors. Dr Kamila Patel will present a poster on a new area for us, using our lentiviral platform to express FVIII in the lung as a potential treatment for haemophilia.

Two of our PhD students will also be presenting posters. Mike Paul-Smith will be presenting his work of alpha-1-antitrypsin gene therapy and Natasha Davie will present her ongoing work looking at the barriers to successful translation of academic research.


The four abstracts can be viewed here and we will add the pdfs when they become available:-

  1. The Significance of Academia-Industry Collaboration in Translational Research: A Survey of Over 300 PIs Who Have Received Industry Funding. Davie NL et al.
  2. Scalable, Animal-Free, Suspension-Based Production of SIV Lentiviral Vectors. Hyde SC et al.
  3. F/HN Pseudotyped Lentivirus Generates Therapeutically Relevant and Long-Lasting Alpha-1-Antitrypsin Expression in Mouse Lung. Paul-Smith MC et al.
  4. Production of Therapeutically Relevant Levels of FVIII After Transduction of Lungs With F/HN-Pseudotyped Lentivirus. Pytel KM et al. 


The entire Conference schedule is available here, and all the abstracts are publically available here.


Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.


A CFTR Western blot, to confirm protein production in cell culture.


Pellets of DNA following precipitation.


Purifying mRNA from tissue samples.