Consortium Blog

Minicircle v Plasmids. Time to think again.

Minicircles have for a number of years been presented as being superior to simple plasmids for gene therapy applications. In some cases it may be the case, but in a new publication we show that compared to a carefully optimised, clinically tested plasmid design they offer no advantages.

1 year ago



Consortium Scientists Shake Things Up at BSGCT Public Education Day

Approximately 300 National, Higher and Advanced Higher students, GCSE and A-level students attended the University of Strathclyde Technology & Innovation Centre for a one day introduction to gene and cell therapy. During the lunchtime break the UK Cystic Fibrosis Gene Therapy Consortium provided hands on activities for pupils at an exhibitor stand. We used a quick and easy protocol to extract DNA using strawberries, detergent, salt and alcohol.

1 year ago



A Raspberry Pi Gel Imager for Less that 100

Buy a new gel imager? No way - lets build our own.

2 years ago




A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.


Proposed 3D model of the CFTR protein.


Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).


Large scale lentivirus production in suspension culture.