Presentation of Multi Dose Clinical Trial Results (2015): Prof Eric Alton presents the data from our MD clinical trial to an invited audience from the UK CF community. May 30 2015, Imperial College, London.
Large scale lentivirus production in suspension culture.
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
A cake that only some of us got to enjoy!
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).
A CFTR Western blot, to confirm protein production in cell culture.
Schematic diagram of the large human airways.
DNA fragments being cut from an agarose gel exposed to UV.
A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.
Proposed 3D model of the CFTR protein.
Pellets of DNA following precipitation.
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.
Purifying mRNA from tissue samples.
Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).