Lentiviral Production in Wave Bioreactor (2015): Suspension cell culture is used to produce large quantities of Lentiviral vector. The rocking platform generates a 'wave' in the disposable bag which keeps cells in suspension.
A cake that only some of us got to enjoy!
Schematic diagram of the large human airways.
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
DNA fragments being cut from an agarose gel exposed to UV.
A CFTR Western blot, to confirm protein production in cell culture.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
Pellets of DNA following precipitation.
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).
Purifying mRNA from tissue samples.
Large scale lentivirus production in suspension culture.
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)