Papers 9

  1. HIV-1 Tat protein transduction domain peptide facilitates gene transfer in combination with cationic liposomes.
    Hyndman L et al., J Control Release. 2004 Oct 19;99(3):435-44.
  2. Intravenously administered oligonucleotides can be delivered to conducting airway epithelium via the bronchial circulation.
    Holder E et al., Gene Ther. 2006 Dec;13(23):1628-38. Epub 2006 Jun 22.
  3. Anti-inflammatory gene therapy directed at the airway epithelium.
    Griesenbach U et al., Gene Ther. 2000 Feb;7(4):306-13.
  4. A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis.
    Gill DR et al., Gene Ther. 1997 Mar;4(3):199-209.
  5. The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro.
    Stern M et al., Gene Ther. 1998 Jan;5(1):91-8.
  6. CFTR gene transfer reduces the binding of Pseudomonas aeruginosa to cystic fibrosis respiratory epithelium.
    Davies JC et al., Am J Respir Cell Mol Biol. 1997 Jun;16(6):657-63.
  7. Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10-CFTR2.
    MacVinish LJ et al., J Physiol. 1997 Mar 15;499 ( Pt 3):677-87.
  8. A second dose of a CFTR cDNA-liposome complex is as effective as the first dose in restoring cAMP-dependent chloride secretion to null CF mice trachea.
    Goddard CA et al., Gene Ther. 1997 Nov;4(11):1231-6.
  9. Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis.
    Hyde SC et al., Gene Ther. 2000 Jul;7(13):1156-65.

 

Schematic diagram of the large human airways.

 

A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.