Papers 8

  1. Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity.
    Holder E et al., J Gene Med. 2010 Jan;12(1):55-63. doi: 10.1002/jgm.1413.
  2. Elimination of contaminant Escherichia coli chromosomal DNA from preparations of P1 artificial chromosome recombinants facilitates directed subcloning.
    Davidson H et al., Electrophoresis. 1999 Jun;20(7):1469-75.
  3. pSURF-2, a modified BAC vector for selective YAC cloning and functional analysis.
    Boyd AC et al., Biotechniques. 1999 Jul;27(1):164-70, 172, 175.
  4. Tripod-like cationic lipids as novel gene carriers.
    Unciti-Broceta A et al., J Med Chem. 2008 Jul 24;51(14):4076-84. doi: 10.1021/jm701493f. Epub 2008 Jun 26.
  5. Differential global gene expression in cystic fibrosis nasal and bronchial epithelium.
    Ogilvie V et al., Genomics. 2011 Nov;98(5):327-36. doi: 10.1016/j.ygeno.2011.06.008. Epub 2011 Jul 2.
  6. The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways.
    Griesenbach U et al., Biomaterials. 2010 Mar;31(9):2665-72. doi: 10.1016/j.biomaterials.2009.12.005. Epub 2009 Dec 21.
  7. Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung.
    McLachlan G et al., Gene Ther. 2011 Oct;18(10):996-1005. doi: 10.1038/gt.2011.55. Epub 2011 Apr 21.
  8. Limitations of the murine nose in the development of nonviral airway gene transfer.
    Griesenbach U et al., Am J Respir Cell Mol Biol. 2010 Jul;43(1):46-54. doi: 10.1165/rcmb.2009-0075OC. Epub 2009 Jul 31.

 

Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).

 

Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.