Laboratory Automation (2007): Our Biomek NX is used to purify RNA/DNA from samples and also to setup a range of assays in the lab. The precision of the 'robot' is greater than human pipetting and allows us to massively increase the throughput of sample processing.
DNA fragments being cut from an agarose gel exposed to UV.
A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
Proposed 3D model of the CFTR protein.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).
Schematic diagram of the large human airways.
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.
Large scale lentivirus production in suspension culture.
A cake that only some of us got to enjoy!
Pellets of DNA following precipitation.
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)
A CFTR Western blot, to confirm protein production in cell culture.
Purifying mRNA from tissue samples.