Laboratory Automation (2007): Our Biomek NX is used to purify RNA/DNA from samples and also to setup a range of assays in the lab. The precision of the 'robot' is greater than human pipetting and allows us to massively increase the throughput of sample processing.
Proposed 3D model of the CFTR protein.
Large scale lentivirus production in suspension culture.
A frozen vial of GL67A (left) and a frozen vial of pGM169 plasmid DNA (right)
A cake that only some of us got to enjoy!
Light microscope image of a human airway liquid interface cultures. Dark patches are mucous.
Human airway liquid interface cultures transduced with a lentivirus expressing Luciferase.
E.coli from a large scale industrial production of our clinical trial plasmid pGM169.
A CFTR Western blot, to confirm protein production in cell culture.
Schematic diagram of the large human airways.
A pellet of E.coli containing a plasmid expressing a pink fluorescent protein.
DNA fragments being cut from an agarose gel exposed to UV.
Pellets of DNA following precipitation.
Sheep lung parenchyma (cell nuclei blue) transduced with an adenoviral vector (green).
Purifying mRNA from tissue samples.
Mouse lung large airway (cell nuclei blue) transduced with an adenoviral vector (green).